The Lede

Are Psychedelics Right-Wing Now?

迷幻药现在成了右翼的东西?
How the conservative activist Bryan Hubbard, with help from Rick Perry and Joe Rogan, persuaded Trump and the G.O.P. to embrace ibogaine, a psychedelic drug derived from an African shrub.
保守派活动人士布莱恩·哈伯德(Bryan Hubbard)如何在里克·佩里(Rick Perry)和乔·罗根(Joe Rogan)的帮助下,说服特朗普和共和党接受伊博格碱——一种从非洲灌木中提取的迷幻药。
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Illustration by Jackson Gibbs

One evening in May, about thirty guests—oil executives, Navy SEALs, and D.C. political operatives among them—arrived at the Coronado Club, in downtown Houston, where Texas’s ultra-wealthy have converged since the nineteen-fifties. Walking past portraits of nineteenth-century Galveston gentry, they filed into the dining room, where QR codes and envelopes had been placed on tabletops to collect donations for Americans for Ibogaine, a pro-psychedelics nonprofit. As waiters in black suits served steak and peach cobbler, Rick Perry, the former Texas governor and the former Republican Presidential candidate, and the chairman of Americans for Ibogaine, leaped to his feet. In recent years, Perry has refashioned himself into a folksy elder statesman of the psychedelic movement, often describing himself as the “Johnny Appleseed” of plant medicines. Standing in front of a painting of the Rio Grande, Perry spoke about the chain of extraordinary events that had led President Donald Trump to sign an executive order, in April, expediting F.D.A. approval of psychedelic therapies. “I’m a very, very strong man of faith,” Perry said. “It couldn’t have happened without some divine intervention.” Then he bowed his head and blessed the meal.

五月的一个晚上,大约三十位宾客——其中有石油公司高管、海豹突击队员和华盛顿的政治操盘手——来到休斯顿市中心的科罗纳多俱乐部(Coronado Club)。自上世纪五十年代起,德克萨斯州的超级富豪们就常在此聚会。他们走过一幅幅描绘十九世纪加尔维斯顿上流人士的肖像画,鱼贯进入餐厅。餐桌上摆放着二维码和信封,为一个支持迷幻药的非营利组织“美国人支持伊博格碱”(Americans for Ibogaine)募集捐款。身着黑西装的侍者端上牛排和蜜桃馅饼时,前德克萨斯州州长、前共和党总统候选人、该组织主席里克·佩里猛地站起身。近年来,佩里将自己重塑为迷幻药运动中一位平易近人的资深政治家,常把自己比作植物药界的“苹果籽约翰尼”。他站在一幅描绘格兰德河的画作前,讲述了一系列非同寻常的事件,最终促使唐纳德·特朗普总统在四月签署了一项行政命令,加快美国食品药品监督管理局(FDA)对迷幻疗法的审批。“我是一个信仰非常、非常坚定的人,”佩里说,“没有某种神圣的干预,这一切不可能发生。”随后,他低下头,为这顿饭祝福。

A scene like this, unimaginable a decade ago, marks a paradigm shift: increasingly, it is conservative leaders who are embracing research into psychedelics. Ibogaine, in particular—a psychedelic drug derived from an African shrub—has become a cause célèbre for the American right. The drug’s relative obscurity has allowed its champions to shake off the baggage of the nineteen-sixties, and to position its use, not as hippie hedonism but as a medical intervention compatible with patriotic duty and Christian faith. This framing has been remarkably effective at winning the support of red-state governments and securing substantial funding for psychedelic research. Buoyed by a countercultural drift, psychedelics now have more political clout than in any previous chapter of American history.

这样的场景在十年前简直无法想象,它标志着一个范式转变:越来越多拥抱迷幻药研究的,是保守派领袖。尤其是伊博格碱——一种从非洲灌木中提取的迷幻药——已成为美国右翼热衷推动的事业。这种药物相对冷门,使得其拥护者得以摆脱上世纪六十年代的包袱,将其使用定位为一种符合爱国义务和基督教信仰的医疗干预,而非嬉皮士的享乐主义。这种叙事框架在赢得红州政府支持和争取迷幻药研究巨额资金方面,效果显著。受这股反文化潮流的推动,迷幻药如今在美国历史上拥有了前所未有的政治影响力。

The major force behind the ibogaine movement in recent years has been Bryan Hubbard, a Kentucky lawyer and lifelong Republican who co-founded Americans for Ibogaine alongside Perry, and stood behind Trump in the Oval Office during the executive-order signing. Born in Russell County, Virginia, Hubbard was largely raised by his grandfathers, both union coal miners with missing fingers, and still speaks with an Appalachian twang. He spent sixteen years practicing workers’-compensation law in Kentucky—a field that revealed the extent to which the opioid crisis had turned the region into an “apoca-billy hillscape,” as he put it. After taking depositions from hundreds of people who had been debilitated by painkillers prescribed for their work injuries, Hubbard came to see addiction not as a moral failure but as the most visible symptom of a profound spiritual affliction at America’s core.

近年来,伊博格碱运动背后的主要推手是布莱恩·哈伯德。他是肯塔基州的一名律师,终身共和党人,与佩里共同创立了“美国人支持伊博格碱”。特朗普签署行政命令时,他就站在椭圆形办公室的总统身后。哈伯德出生在弗吉尼亚州的拉塞尔县,主要由两位祖父抚养长大,他们都是手指残缺的工会煤矿工人,至今说话仍带着阿巴拉契亚口音。他在肯塔基州做了十六年的工伤赔偿律师——这个领域让他看到,阿片类药物危机已将这个地区变成了他所说的“末日乡巴佬荒原”。在听取了数百名因工伤服用止痛药而致残者的证词后,哈伯德逐渐认识到,成瘾并非道德缺陷,而是美国核心地带一种深刻精神痛苦的最明显症状。

Hubbard went on to run Kentucky’s Social Security disability system and its child-support-enforcement program, before leading its Office of Medicaid Fraud and Abuse Control. In 2022, the attorney general Daniel Cameron appointed him to lead Kentucky’s newly formed opioid-abatement program, which was charged with distributing roughly half of the eight hundred and forty-two million dollars that the state had received from a settlement with opioid companies. After steering some of the funds toward naloxone and addiction-treatment programs, Hubbard began researching alternative rehabilitation therapies. He first learned about ibogaine from Julia Reibelt, the author of a popular Substack about her experiences with psychedelic therapy. Ibogaine has been used for decades in international clinics and underground circles to treat severe drug addiction; unlike psychedelics such as psilocybin, it has a reputation for mitigating acute opioid-withdrawal symptoms. Intrigued, Hubbard later flew to New York, where he grew convinced of the drug’s potential after meeting with leading ibogaine researchers, veteran advocates, and philanthropists. He spent the following months organizing a series of public hearings in Kentucky where F.D.A. officials, Stanford researchers, and U.S. military veterans testified about ibogaine’s benefits. But, just as Hubbard was on the cusp of allocating forty-two million dollars from the opioid settlement to ibogaine clinical trials, Cameron, his political benefactor, was replaced in the A.G.’s office by Russell Coleman, a former F.B.I. agent. Displeased with Hubbard’s ibogaine advocacy, Coleman called him into a meeting where, according to Hubbard, he was “ambushed” and asked to resign. (Coleman cited “limited resources” as part of the reasoning behind his opposition, and said that the state should be more focussed on the prevention side of the opioid crisis.)

哈伯德后来管理过肯塔基州的社会保障残疾系统和儿童抚养执行项目,之后又领导了该州的医疗补助欺诈与滥用控制办公室。2022年,司法部长丹尼尔·卡梅伦(Daniel Cameron)任命他领导肯塔基州新成立的阿片类药物消减项目,负责分配该州与阿片类药物公司达成和解后获得的八亿四千二百万美元中的大约一半。在将部分资金用于纳洛酮和成瘾治疗项目后,哈伯德开始研究替代性康复疗法。他最初是从茱莉亚·雷贝尔特(Julia Reibelt)那里了解到伊博格碱的,雷贝尔特在Substack上写了一个很受欢迎的博客,分享她接受迷幻疗法的经历。几十年来,伊博格碱一直在国际诊所和地下圈子里被用于治疗严重药物成瘾;与裸盖菇素等迷幻药不同,它以能缓解急性阿片类药物戒断症状而闻名。哈伯德很感兴趣,后来飞到纽约,在与顶尖的伊博格碱研究人员、资深倡导者和慈善家会面后,他越发确信这种药物的潜力。接下来的几个月,他在肯塔基州组织了一系列公开听证会,FDA官员、斯坦福大学的研究人员和美国退伍军人在会上就伊博格碱的益处作证。但就在哈伯德即将从阿片类药物和解金中拨出四千二百万美元用于伊博格碱临床试验之际,他的政治恩主卡梅伦被前联邦调查局探员拉塞尔·科尔曼(Russell Coleman)取代了司法部长一职。科尔曼对哈伯德倡导伊博格碱感到不满,把他叫去开会。据哈伯德说,他在会上遭到了“伏击”,并被要求辞职。(科尔曼将“资源有限”作为其反对的部分理由,并表示州政府应更专注于阿片类药物危机的预防方面。)

Hubbard was undeterred. He started working with the REID Foundation, a nonprofit founded by the G.O.P. operative Rex Elsass in honor of his son, who died of an overdose, to keep the cause alive. He met with elected officials as well as academic researchers in other states such as Washington and New Mexico, and came very close to getting an initiative off the ground in South Dakota, under then governor Kristi Noem, but days before making a formal announcement, budget constraints stymied the effort.

哈伯德并未气馁。他开始与REID基金会合作,以维持这项事业。该基金会由共和党操盘手雷克斯·埃尔萨斯(Rex Elsass)创立,以纪念他因吸毒过量而死的儿子。他会见了民选官员以及其他州(如华盛顿州和新墨西哥州)的学术研究人员,并差一点在南达科他州时任州长克里斯蒂·诺姆(Kristi Noem)的领导下启动了一项计划,但在正式宣布的前几天,预算限制使这项努力受挫。

Eventually, in the wake of that disappointment, Hubbard found Logan Davidson, the senior adviser of Texans for Greater Mental Health and the director of policy and advocacy of Veterans Exploring Treatment Solutions. In 2021, Davidson had successfully shepherded the bill that made Texas the first state to fund psychedelic research, for psilocybin-assisted therapy for veterans—a precedent that Hubbard thought could open a path forward for ibogaine. And, while other states had balked at the fifty-million-dollar price tag that Hubbard deemed necessary for the clinical trials, Texas had ended the year with a twenty-four-billion-dollar budget surplus from oil and gas revenues. “Texas needs to finish the job I began in Kentucky,” Hubbard told Davidson. But first he had to make one call.

最终,在那次失望之后,哈伯德找到了洛根·戴维森(Logan Davidson),他是“德州人争取更佳心理健康”组织的高级顾问,也是“退伍军人探索治疗方案”组织的政策与倡导主任。2021年,戴维森成功推动了一项法案,使德克萨斯州成为第一个资助迷幻药研究(针对退伍军人的裸盖菇素辅助治疗)的州——哈伯德认为这个先例可以为伊博格碱开辟一条前进的道路。而且,当其他州对哈伯德认为临床试验所必需的五千万美元标价犹豫不决时,德克萨斯州年底却从石油和天然气收入中获得了二百四十亿美元的预算盈余。“德克萨斯州需要完成我在肯塔基州开始的工作,”哈伯德告诉戴维森。但首先,他得打一个电话。

In September, 2023, after decades of suppressing anxiety and insomnia that he partially attributed to severe concussions he suffered as a high-school quarterback, Rick Perry went to a clinic outside Tijuana, where he lay down on a mattress, pulled on an eye mask, and started tripping on ibogaine. “I was on a spaceship, and there were all these Mesoamerican symbols and hieroglyphics flying past me,” he told me, by phone, from his ranch in Round Top, Texas. “Out in the distance, one that caught my attention was Satan.” The demon had “little horns” and “baying teeth,” but Perry felt no fear. “He came up right in front of me, and I said, ‘Satan, get behind me,’ ” Perry said. “He did disappear.”

2023年9月,在压抑了数十年的焦虑和失眠之后——里克·佩里将其部分归因于高中担任四分卫时遭受的严重脑震荡——他去了蒂华纳郊外的一家诊所。在那里,他躺在一张床垫上,戴上眼罩,开始体验伊博格碱带来的迷幻之旅。“我上了一艘宇宙飞船,各种中美洲的符号和象形文字从我身边飞过,”他在德克萨斯州圆顶镇的牧场里通过电话告诉我。“远处,一个引起我注意的是撒旦。”那个恶魔长着“小角”和“龇出的牙”,但佩里并不感到恐惧。“他径直来到我面前,我说:‘撒旦,退到我身后去,’”佩里说。“他真的消失了。”

At the same clinic, he smoked 5-MeO-DMT—a highly potent psychedelic that can be found in the venom of the Colorado River toad—which provoked a sort of spiritual ecstasy. “It was clearly the brightest, whitest, purest light that I’ve ever been around in my life,” he told me. “I knew that I was in the presence of God, and that he loved me immeasurably.”

在同一家诊所,他吸入了5-MeO-DMT——一种效力极强的迷幻药,可在科罗拉多河蟾蜍的毒液中发现——这引发了一种精神上的狂喜。“那无疑是我一生中见过的最明亮、最洁白、最纯净的光,”他告诉我。“我知道自己就在上帝面前,他无限地爱着我。”

Perry said that an MRI taken before the trip showed mild brain atrophy, typical of a man in his seventies; another scan, taken six months later, showed none at all, and he recalled his neurosurgeon, Charles Gordon, telling him that he now had the brain of a forty-year-old. Countless veterans whom Perry had gotten to know had experienced similarly stark recoveries after exhausting conventional treatments for brain injuries and trauma, and turning to ibogaine. Between these firsthand testimonies from veterans, his own medical miracle, and the spiritual experience, Perry became convinced that helping legitimize ibogaine should be his life’s mission. He understood psychedelics to be a reification of the Christian belief in life after death. That belief seemed especially potent the day we spoke—thirty minutes before our interview, he’d discovered that one of his five dogs had died. “I got most of my crying out,” Perry said, emotion still heavy in his voice. “This medicine is, for me, a confirming message that, after death, your spiritual home is waiting on you. There’s nothing to be afraid of,” he said, slowly. Then a long pause. “I get to see my dog.”

佩里说,迷幻之旅前做的核磁共振显示他有轻度脑萎缩,这对七十多岁的男性来说很典型;而六个月后做的另一次扫描则显示脑萎缩完全消失,他回忆起他的神经外科医生查尔斯·戈登(Charles Gordon)告诉他,他现在拥有一个四十岁人的大脑。佩里认识的无数退伍军人,在穷尽了针对脑损伤和创伤的常规治疗后,转向伊博格碱,也经历了同样显著的康复。基于这些退伍军人的第一手证词、他自己的医学奇迹以及精神体验,佩里确信,帮助伊博格碱获得认可应成为他的人生使命。他将迷幻药理解为基督教对死后生命信仰的具体体现。我们交谈那天,这种信仰似乎格外有力——采访前半小时,他发现他的五条狗中有一条死了。“我差不多哭够了,”佩里说,声音里仍带着沉重的情感。“对我来说,这种药是一个确认的信息:死后,你的精神家园在等着你。没什么好怕的,”他缓缓说道。然后是一阵长长的停顿。“我能再见到我的狗了。”

Hubbard and Perry first met in June, 2023, after the ex-governor keynoted a psychedelics conference organized by the Multidisciplinary Association for Psychedelic Studies (MAPS); Hubbard later reached out to him to see if he could assist with the effort to bring ibogaine to Texas. In October, 2024, the two invited thirty handpicked Texans—veterans, researchers, donors—to a war-council-style meeting in downtown Austin. “I’m the football coach, Bryan is the quarterback, and y’all are the team,” Perry told them.

哈伯德和佩里于2023年6月首次见面,当时这位前州长在迷幻药多学科研究协会(MAPS)组织的一次迷幻药会议上发表了主旨演讲;哈伯德后来联系了他,看他能否协助将伊博格碱引入德克萨斯州。2024年10月,两人邀请了三十名精心挑选的德克萨斯人——包括退伍军人、研究人员和捐赠者——到奥斯汀市中心参加一场类似作战会议的聚会。“我是橄榄球教练,布莱恩是四分卫,你们都是队员,”佩里对他们说。

The veterans were a key part of the team. Unlike in Kentucky, where Hubbard pushed ibogaine as a broader treatment for former opioid addicts, the clinical trials that Hubbard, Perry, and Davidson were proposing, in Texas, would be centered on veterans, in keeping with the psilocybin precedent. Rick Doblin, the founder and president of MAPS, had identified, decades earlier, that veterans, as a sympathetic constituency, were the surest route to bipartisan support. He pointed out that ibogaine’s therapeutic potential had been evident since the nineteen-sixties. “But we need to show that the psychedelics are coming to heal people who society values, and we tend to demonize addicts.” He added, “The fact that you can take psychedelics and stay Christian, stay Republican—that’s the key learning that society needed in order to integrate these drugs.”

退伍军人是这个团队的关键部分。与在肯塔基州将伊博格碱作为针对前阿片类药物成瘾者的更广泛疗法不同,哈伯德、佩里和戴维森在德克萨斯州提议的临床试验将以退伍军人为中心,这与裸盖菇素的先例保持一致。MAPS的创始人兼主席里克·多布林(Rick Doblin)几十年前就指出,退伍军人作为一个富有同情心的群体,是获得两党支持最可靠的途径。他指出,伊博格碱的治疗潜力自上世纪六十年代以来就已显现。“但我们需要表明,迷幻药是用来治愈社会所珍视的人的,而我们往往将成瘾者妖魔化。”他补充道,“你可以服用迷幻药,同时保持基督徒身份、保持共和党人身份——这是社会为了整合这些药物所需要的关键认知。”

In the spring of 2025, the team built momentum through activities such as hosting private screenings of “In Waves and War,” a documentary on Navy SEALs and psychedelic therapy, which they used to recruit dozens of legislators to their cause. At one point, they were holding seventy meetings a day; Davidson described the campaign as the most intense experience of his political career. It was also one of the weirdest. “Most legislative and political efforts are pretty homogenous, but this was the strangest cast of characters you can imagine,” he said. “You’re standing up there next to Navy SEALs, career scientists, MAHA hippies, traditional hippies, first responders—everybody is getting in.”

2025年春天,该团队通过举办纪录片《浪与战》(In Waves and War)的私人放映会等活动来积蓄势头。这部关于海豹突击队员和迷幻疗法的纪录片,被他们用来招募了数十名立法者支持他们的事业。有一段时间,他们一天要开七十场会;戴维森形容这场运动是他政治生涯中最紧张的经历。这也是最奇特的经历之一。“大多数立法和政治活动都相当单一,但这次你能想象到的最奇怪的各色人物都聚齐了,”他说。“你站在台上,旁边是海豹突击队员、职业科学家、MAHA嬉皮士、传统嬉皮士、急救人员——所有人都参与进来了。”

That May, Hubbard was invited to a closed-door meeting with Texas’s Speaker of the House, Dustin Burrows, and Lieutenant Governor Dan Patrick, to make his case for fifty million dollars in state appropriations to bring ibogaine to Phase III clinical trials—a sum that even his own team doubted he’d land. Hubbard burned a wish ticket, believed to manifest desires, on the balcony of his hotel room before walking to the state capitol. The meeting had been scheduled to run for thirty minutes. After an hour and a half, Hubbard emerged, with his head down, then looked up at his team, who were standing outside waiting for him. He stomped his foot. “Fifty million fucking dollars,” he said. The confirmation came by text two days later. It was like scoring the winning touchdown in the final minutes of a game.

那年五月,哈伯德受邀与德克萨斯州众议院议长达斯汀·伯罗斯(Dustin Burrows)和副州长丹·帕特里克(Dan Patrick)举行闭门会议,为争取五千万美元的州拨款以推动伊博格碱进入三期临床试验进行游说——这笔钱连他自己的团队都怀疑他能否拿到。在走向州议会大厦之前,哈伯德在他酒店房间的阳台上烧了一张据说能实现愿望的许愿票。会议原定三十分钟。一个半小时后,哈伯德低着头走了出来,然后抬头看向站在外面等他的团队。他跺了跺脚。“五千万他妈的美金,”他说。两天后,确认短信到了。这就像在比赛最后几分钟达阵得分,赢得胜利。

In June, 2025, Governor Greg Abbott signed Senate Bill 2308, creating a framework for ibogaine clinical trials funded by partnerships between the state and private drug developers. The bill passed the Texas House 138–2, and the state Senate 27–4. By December, a consortium led by UTHealth Houston and U.T.M.B. Health had been awarded the fifty-million-dollar sum to lead the trials. “Democrats early on were, like, Yes, we support this, but we’re not going to get tagged as the druggies,” Davidson said. “That’s where the conservative influence provides cover. Each side gets permission from the other side to do this.” Hubbard told me that he hopes the win becomes a “big-bang singularity” which other red states will follow. Today, nineteen states have pro-psychedelic legislation passed or pending, including Arizona, Oklahoma, and West Virginia.

2025年6月,州长格雷格·阿博特(Greg Abbott)签署了参议院第2308号法案,为伊博格碱临床试验创建了一个由州政府和私人药物开发商合作资助的框架。该法案在德克萨斯州众议院以138票对2票通过,在州参议院以27票对4票通过。到十二月,由德克萨斯大学休斯顿健康科学中心(UTHealth Houston)和德克萨斯大学医学分部(U.T.M.B. Health)牵头的联合体获得了五千万美元的资金,负责领导这些试验。“民主党人一开始就说,是的,我们支持这个,但我们不想被贴上瘾君子的标签,”戴维森说。“这就是保守派影响力提供掩护的地方。每一方都从另一方那里获得了做这件事的许可。”哈伯德告诉我,他希望这场胜利能成为一个“大爆炸奇点”,其他红州将会效仿。如今,已有十九个州通过或正在审议支持迷幻药的立法,包括亚利桑那州、俄克拉荷马州和西弗吉尼亚州。

The city of Austin, meanwhile, “is the psychedelic center of the world at this point,” Paul Austin, the host of the “Third Wave” podcast and a microdosing coach for the entrepreneurial class, told me. A new archetype has emerged from this scene: the rugged libertarian cowboy. In March, at an Americans for Ibogaine event held during SXSW week at a MAHA-adjacent wellness club in Austin, Hubbard, who sports a thick beard and shoulder-length hair, showed up in bluejeans and cowboy boots. Standing onstage near a refrigerator of raw milk, as the scent of barbecue wafted in the air, he delivered a fiery speech outlining ibogaine’s emancipatory potential for the American people, channelling a Western sheriff’s incorruptible sense of justice and a preacher’s thundering conviction. Describing veterans as “ground zero” for addiction and suicide, Hubbard noted that “deaths of despair” have taken a million and a half American lives in the past ten years, a figure he said exceeds the number of U.S. soldiers killed in action since 1776. “I don’t care what culture you come from, what color you are, or what your political-party label is,” he said. “We can look at the foundations of this country as they are now, and we see the crumbling and the cracking and the strain,” he continued, his voice rising. “Yes, this is about ibogaine. But this is about the human condition, and what this country is supposed to be.”

与此同时,奥斯汀市“现在是世界的迷幻药中心,”保罗·奥斯汀(Paul Austin)告诉我。他是“第三波”播客的主持人,也是一位为企业主阶层服务的微剂量教练。这个圈子涌现出一种新的原型:粗犷的自由意志主义牛仔。三月,在西南偏南大会(SXSW)期间,于奥斯汀一家靠近MAHA理念的健康俱乐部举行的“美国人支持伊博格碱”活动上,留着浓密胡须和齐肩长发的哈伯德,穿着蓝色牛仔裤和牛仔靴现身。他站在舞台上,旁边是一台装满生牛奶的冰箱,空气中飘着烧烤的香味。他发表了一篇激昂的演讲,阐述了伊博格碱对美国人民的解放潜力,言语间流露出西部警长那不可腐蚀的正义感和牧师般雷鸣般的信念。他将退伍军人描述为成瘾和自杀的“原爆点”,并指出过去十年中,“绝望之死”已夺走了一百五十万美国人的生命,他说这个数字超过了自1776年以来美军阵亡士兵的总数。“我不在乎你来自什么文化,是什么肤色,或者你的政党标签是什么,”他说。“我们可以审视这个国家现在的根基,我们看到的是崩裂、破碎和压力,”他继续说道,声音越来越高。“是的,这关乎伊博格碱。但这关乎人类的处境,关乎这个国家本应成为的样子。”

About two weeks later, Hubbard and Perry sat down with Joe Rogan, in his podcast studio, in Austin, for the second time. Their first conversation with Rogan introduced ibogaine to more than a million and a half viewers on YouTube, but their second appearance would prove even more consequential. As Perry told this story to the Coronado Club audience, back in May, he paused for dramatic effect. “Here’s what’s happened,” he said. “We’re standing in the studio, microphones off. Joe Rogan says, ‘What can I do to help you?’ And Bryan said, ‘Talk to the President.’ It was really that simple. Rogan—I hug his neck, man—this guy literally texted the President.”

大约两周后,哈伯德和佩里在奥斯汀乔·罗根的播客录音室里,第二次与罗根对谈。他们与罗根的第一次对话向YouTube上超过一百五十万观众介绍了伊博格碱,但他们的第二次亮相被证明更具影响力。五月,当佩里在科罗纳多俱乐部向听众讲述这个故事时,他为了戏剧效果停顿了一下。“事情是这样的,”他说。“我们站在录音室里,麦克风关着。乔·罗根说:‘我能帮你们做点什么?’布莱恩说:‘跟总统谈谈。’真的就这么简单。罗根——我真想拥抱他,老兄——这家伙直接给总统发了短信。”

According to Hubbard, Rogan sent Trump information about ibogaine’s treatment outcomes for addicts and veterans suffering from P.T.S.D. When Rogan saw Trump at a U.F.C. fight in Miami, on April 11th, the President told Rogan that he thought ibogaine was a good idea. After that, things moved quickly. On April 18th, Hubbard was at the White House for the executive-order signing, which he described as an “out-of-body psychedelic experience.” Rogan opened with remarks about how the War on Drugs campaign was racist as Trump stared ahead impassively. Then Rogan told reporters Trump’s reply when he first texted him about ibogaine: “Sounds great. Do you want F.D.A. approval? Let’s do it.” As the camera panned between Robert F. Kennedy, Jr., and Dr. Mehmet Oz, Trump solicited testimonials about how great ibogaine is—then briefly pivoted to Iran, before coming back to sign the order. “Can I have some, please?” Trump joked, while struggling to pronounce the word “ibogaine.” He went on, “I’ll take whatever it takes. I don’t have time to be depressed.” It was the first time that a sitting U.S. President had spoken favorably about psychedelics.

据哈伯德说,罗根向特朗普发送了关于伊博格碱对成瘾者和患有创伤后应激障碍(PTSD)的退伍军人治疗效果的信息。4月11日,当罗根在迈阿密的一场终极格斗冠军赛(UFC)上见到特朗普时,总统告诉罗根,他认为伊博格碱是个好主意。此后,事情进展迅速。4月18日,哈伯德在白宫参加了行政命令的签署仪式,他将此描述为一次“灵魂出窍的迷幻体验”。罗根开场便谈到“禁毒战争”是种族主义的,而特朗普面无表情地凝视着前方。随后,罗根告诉记者,当他第一次就伊博格碱给特朗普发短信时,特朗普回复说:“听起来很棒。你想要FDA批准吗?那就干吧。”当镜头在小罗伯特·F·肯尼迪(Robert F. Kennedy, Jr.)和穆罕默德·奥兹医生(Dr. Mehmet Oz)之间切换时,特朗普征求关于伊博格碱有多好的证言——然后短暂地转向了伊朗问题,之后又回来签署了命令。“能给我来点吗?”特朗普开玩笑说,同时费力地念着“伊博格碱”这个词。他接着说,“需要什么我就来什么。我可没时间抑郁。”这是美国在任总统首次对迷幻药发表正面言论。

The executive order, titled “Accelerating Medical Treatments for Serious Mental Illness,” directs federal agencies to improve coördination and reduce delays around psychedelic clinical trials and drug development; it also states that patients with life-threatening conditions can access these investigational drugs under the Right to Try Act. The order’s singling out of ibogaine, the only psychedelic mentioned by name, surprised analysts, given how much less research exists on it than on psilocybin or MDMA. “It really couldn’t have been based solely or even primarily on science, because the science is just so lacking,” Mason Marks, a law professor at Michigan State University who specializes in F.D.A.and controlled-substances regulation, told me.

这项名为“加速严重精神疾病的医学治疗”的行政命令,指示联邦机构改善协调,减少迷幻药临床试验和药物开发方面的延误;它还规定,患有危及生命疾病的患者可以根据“尝试权法案”获得这些研究性药物。该命令特别点名了伊博格碱,这是唯一被提及名称的迷幻药,这让分析人士感到惊讶,因为与裸盖菇素或MDMA相比,关于它的研究要少得多。“这真的不可能仅仅甚至主要基于科学,因为科学依据实在太缺乏了,”密歇根州立大学专攻FDA和管制药物监管的法学教授梅森·马克斯(Mason Marks)告诉我。

Hubbard and Perry call ibogaine “the most sophisticated molecule on the planet,” and often cite a 2024 Stanford study that found sharp reductions in P.T.S.D., depression, and anxiety symptoms among thirty Special Operations veterans with a history of traumatic brain injury. However, given the legal limitations, studies like the Stanford one are observational and limited to small groups, and the science behind ibogaine’s supposedly miraculous workings remains thin. Also, ibogaine’s prolongation of the heart’s QT intervals carries a real risk of fatal arrhythmia. “This cardiotoxicity continues to be a concern, but researchers have developed protocols to try to address it,” Nora Volkow, the longtime director of the National Institute on Drug Abuse, told me.

哈伯德和佩里称伊博格碱为“地球上最复杂的分子”,并经常引用2024年斯坦福大学的一项研究,该研究发现,三十名有创伤性脑损伤史的特种作战退伍军人的PTSD、抑郁和焦虑症状显著减轻。然而,鉴于法律限制,像斯坦福这样的研究只是观察性的,且局限于小群体,伊博格碱所谓神奇疗效背后的科学依据仍然薄弱。此外,伊博格碱会延长心脏的QT间期,存在导致致命性心律失常的真实风险。“这种心脏毒性仍然是一个担忧,但研究人员已经制定了方案来尝试解决它,”美国国家药物滥用研究所(National Institute on Drug Abuse)的长期负责人诺拉·沃尔科夫(Nora Volkow)告诉我。

Marks and other legal experts noted that the executive order’s actual provisions are fairly modest, and in some cases even unnecessary, like speeding up F.D.A. approval for reclassifying Schedule 1 drugs—this already happens by law within three months of F.D.A. approval. “It’s like condensing the last mile by a fraction,” Marks said, explaining that it’s the requirement for extensive clinical trials that makes the process so lengthy. And, although stock prices for drug companies researching psychedelics soared in reaction to the news, it remains unclear whether the order will actually expedite F.D.A. approval for such drugs. Matt Zorn, an H.H.S. lawyer with a background in psychedelics policy who drafted much of the order, pushed back at criticisms. “Just because it’s symbolic doesn’t mean it’s not functional,” he told me. “An executive order forces something to the top of the agenda that may have languished at the bottom.”

马克斯和其他法律专家指出,该行政命令的实际条款相当温和,在某些情况下甚至是不必要的,比如加快FDA对重新分类一类管制药物的审批——这在法律上本就会在FDA批准后的三个月内完成。“这就像把最后一英里缩短了一小截,”马克斯说,他解释说,让整个过程如此漫长的是对大规模临床试验的要求。而且,尽管研究迷幻药的制药公司股价因这一消息而飙升,但该命令是否真的会加快FDA对此类药物的审批仍不清楚。卫生与公众服务部(HHS)律师马特·佐恩(Matt Zorn)拥有迷幻药政策背景,他起草了该命令的大部分内容,并对批评意见进行了反驳。“仅仅是象征性的,并不意味着它不起作用,”他告诉我。“一项行政命令会迫使某件事被提上议程的首位,而这件事可能一直在底部徘徊。”

The most tangible provision was the directing of tens of millions of dollars in federal funding to support state governments with psychedelic-research programs—a move that implicitly favored Texas, the only state at that point with a framework and state-sanctioned funds to conduct ibogaine research. Four weeks later, Colorado launched its own ibogaine initiative, which Perry attributes to his conversations with Governor Jared Polis. The movement, as Hubbard hoped, had begun to spread.

最实质性的条款是,指示将数千万美元的联邦资金用于支持拥有迷幻药研究项目的州政府——这一举措含蓄地有利于德克萨斯州,因为它是当时唯一拥有进行伊博格碱研究的框架和州政府批准资金的州。四周后,科罗拉多州启动了自己的伊博格碱计划,佩里将此归功于他与州长贾里德·波利斯(Jared Polis)的对话。正如哈伯德所希望的那样,这场运动已经开始蔓延。

Back at the Coronado Club, over dessert, a guest raised what he saw as the central contradiction of the evening: preaching “just say no” to kids while the attendees sat at a fund-raiser for ibogaine. “Most of the people in this room are probably conservative, and we’ve had to take a position that is almost the opposite of where we were, say, five years ago,” he said.

回到科罗纳多俱乐部,吃甜点时,一位宾客提出了他眼中当晚的核心矛盾:一边教导孩子们“对毒品说不”,一边在座的人却坐在伊博格碱的筹款会上。“这个房间里的大多数人可能都是保守派,我们不得不采取一个几乎与五年前立场相反的立场,”他说。

Perry clarified his position. “I am still anti-drugs, recreationally,” he said. “I am very much against the legalization of drugs.” Rather, he was advocating for these psychedelics to be rescheduled so that they could be researched, with the ultimate goal of dispensing psychedelic treatments under the health-care system with the same oversight as prescription medications. But other members of Texas’s conservative establishment were still dubious. “They don’t do that, and go to a concert?” a woman asked, of the drugs in question. Another guest unintentionally hit on one of the movement’s main unresolved tensions when he asked where ibogaine came from, and how its supply would be controlled long term.

佩里澄清了他的立场。“我仍然反对娱乐性吸毒,”他说。“我非常反对毒品合法化。”相反,他主张将这些迷幻药重新分类,以便进行研究,最终目标是在医疗保健系统下,像处方药一样,在同样的监管下提供迷幻治疗。但德克萨斯州保守派建制派的其他成员仍持怀疑态度。“他们不会吃了那个,然后去听音乐会吧?”一位女士问到那些药物。另一位宾客无意中触及了该运动一个尚未解决的主要矛盾,他问伊博格碱来自哪里,以及其供应将如何长期控制。

After the executive order, a coalition of ibogaine practitioners had published an open letter warning of the risks of overharvesting the iboga plant and cutting out the Bwiti people of Gabon, who have used it ceremonially for generations. Hubbard told guests at the Coronado Club that his movement leans on both science and reverence. He noted that there is the capacity to create a self-contained, U.S.-based supply chain through yeast and algae that replicate ibogaine’s alkaloid. Meanwhile, pharmaceutical companies are trying to develop an oral version of noribogaine, ibogaine’s primary metabolite, and other companies are working on non-psychoactive derivatives. But he also insisted that there was still much to learn from the Bwiti. “They are the possessors of what I would call the master key of knowledge,” Hubbard said. He said that one of his main priorities is “making sure that they are involved, and can deliver what they have known now for centuries.” In return, he said, U.S. researchers would offer “scientific knowledge on things that can help improve life there,” and the Bwiti would “be our full partner for the medicalization of Ibogaine in the U.S. and globally.” Whether that priority can survive the process of medicalizing ibogaine remains an open question. “Here’s the other reality,” he said, his voice lowering. “The systems that have fought the emergence of ibogaine specifically, and psychedelic medicine generally, over the past sixty years are now the same systems that are going to shepherd their emergence.” ♦

行政命令发布后,一个伊博格碱从业者联盟发表了一封公开信,警告过度采伐伊博格植物的风险,以及将加蓬的布维蒂人(Bwiti)排除在外的风险,他们世代在仪式中使用这种植物。哈伯德在科罗纳多俱乐部告诉宾客,他的运动既依靠科学,也依靠敬畏之心。他指出,有能力通过复制伊博格碱生物碱的酵母和藻类,创建一个自给自足的、基于美国的供应链。与此同时,制药公司正试图开发伊博格碱主要代谢物去甲伊博格碱的口服版本,其他公司则在研究非精神活性的衍生物。但他也坚持认为,仍有很多东西要向布维蒂人学习。“他们是我称之为知识万能钥匙的拥有者,”哈伯德说。他说,他的主要优先事项之一是“确保他们参与进来,并能传递他们几个世纪以来已知晓的东西。”作为回报,他说,美国研究人员将提供“能够帮助改善那里生活的科学知识”,而布维蒂人将“成为我们在美国和全球将伊博格碱医学化的全面合作伙伴。”这一优先事项能否在伊博格碱医学化的过程中幸存下来,仍是一个悬而未决的问题。“另一个现实是,”他压低声音说,“过去六十年来一直阻碍伊博格碱,乃至整个迷幻药出现的体系,如今正是将要引导它们出现的体系。” ♦

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